Genomics Research & Biomarkers for Cancer

Genomics Research & Biomarkers

Genomics Research & Biomarkers

What is Genomics Research & Biomarkers?

Genomics is the study of the complete genetic makeup of organisms, including gene sequences, structures, functions, and interactions. Cancer genomics aims to identify genetic alterations driving tumorigenesis and affecting treatment responses to develop biomarkers for early detection, prognosis, and therapy selection. 

Key areas include mapping genetic mutations, studying gene expression patterns, epigenetic profiling, genome sequencing, and genome-wide association studies linking genetic variants to cancer risk. Biomarkers are measurable indicators of biological states used to guide disease diagnosis, monitoring, and treatment strategies.

NFCR IMPACTS IN GENOMICS RESEARCH & BIOMARKERS RESEARCH

  • NFCR funds development of advanced sequencing techniques like single cell RNA-seq to unravel tumor heterogeneity.
  • NFCR supports translational research to move newly discovered biomarkers from bench to clinical implementation.
  • NFCR’s research grants have enabled studies correlating genomic alterations with treatment response to guide more precise therapeutic selection.
  • NFCR provides bridge funding to researchers exploring high-risk, high-reward ideas that could accelerate progress in the field.

NFCR-Supported Researchers Working on Genomics Research & Biomarkers

Lisa Coussens, Ph.D.
Oregon Health & Science University

Elana Fertig, Ph.D
Johns Hopkins University
Sidney Kimmel Comprehensive Cancer Center

Aaron N. Hata, M.D., Ph.D.
Harvard Medical School and
Massachusetts General Hospital

Jessica J. Lin, M.D.

Jessica J. Lin, M.D.
Harvard Medical School and
Massachusetts General Hospital

Teresa Davoli, Ph.D
New York University School of Medicine

J. Silvio Gutkind, Ph.D
University of California San Diego

Danny R. Welch, Ph.D.
University of Kansas Cancer Center

Isidore Rigoutsos, Ph.D.
University Sidney Kimmel Cancer Center

Daniel A. Haber, M.D., Ph.D.
Massachusetts General Hospital Cancer Center

Esther Rheinbay, Ph.D.
Massachusetts General Hospital Cancer Center, Harvard Medical School

Himisha Beltran, M.D.
Dana-Farber Cancer Institute
Harvard Medical School

Srinivas Vaswanathan, M.D., Ph.D.
Associate Professor of Medicine, Harvard Medical School

Ritesh R. Kotecha, M.D.

Ritesh R. Kotecha, M.D.
Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine

Christian Rolfo, M.D., Ph.D.

Christian Rolfo, M.D., Ph.D.
Associate Director Clinical Research, Center for Thoracic Oncology
Icahn School of Medicine at Mount Sinai

Ling Huang, Ph.D.

Ling Huang, Ph.D.
Pancreatic Cancer Center,
Henry Ford Cancer Institute
Henry Ford Health System

Aditya Bardia, M.D.

Aditya Bardia, M.D.
Massachusetts General Hospital & Harvard Medical School

Massimo Cristofanilli, M.D.
Professor of Medicine, Chief of Breast Medical Oncology
Weill Cornell Medicine

Benjamin Drapkin, M.D., Ph.D.

Benjamin Drapkin, M.D., Ph.D.
Hematology/Medical Oncology
UT Southwestern Medical Center

Darren Carpizo, M.D., Ph.D.

Darren Carpizo, M.D., Ph.D.
University of Rochester

Igor Astsaturov, M.D., Ph.D.

Igor Astsaturov, M.D., Ph.D.
Fox Chase Cancer Center

David H. Peng, Ph.D.

David H. Peng, Ph.D.
The University of Texas MD Anderson Cancer Center

Cesare Spadoni, Ph.D., M.B.A.
University of London

Paul Fisher, M.Ph., Ph.D.

Paul Fisher, M.Ph., Ph.D.
Virginia Commonwealth University

Bert Vogelstein, M.D.

Bert Vogelstein, M.D.
Clayton Professor of Oncology
Co-Director of the Ludwig Center at Johns Hopkins Kimmel Cancer Center
The Johns Hopkins University

Curt Civin, M.D.

Curt I. Civin, M.D.
University of Maryland School of Medicine

 

Wei Zhang, Ph.D

Wei Zhang, Ph.D.
Wake Forest Baptist Medical Center

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